Description

(S)-(-)-2-Methyl-2-Propanesulfinamide CAS NO 343338-28-3 is a high-purity chiral sulfinamide, widely recognized as a versatile and highly effective chiral auxiliary in asymmetric synthesis. Its primary value lies in enabling the stereoselective construction of carbon-nitrogen and carbon-carbon bonds, which is critical for producing enantiomerically pure intermediates. This compound is an essential building block for pharmaceutical R&D and fine chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Employed for the stereoselective synthesis of amines, amino acids, and other nitrogen-containing chiral compounds.
• Pharmaceutical Intermediate: A key starting material or reagent in the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and pesticides where specific stereochemistry is required for bioactivity.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral catalysts and ligands used in transition metal-catalyzed reactions.
• Academic and Industrial R&D: A fundamental tool in research laboratories for methodological development in organic and medicinal chemistry.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	(S)-(-)-2-Methyl-2-Propanesulfinamide
CAS No.	343338-28-3
Molecular Formula	C4H11NOS
Molecular Weight	121.20 g/mol
Synonyms	(S)-tert-Butanesulfinamide; (S)-2-Methylpropane-2-sulfinamide; (S)-(-)-tert-Butylsulfinamide; (S)-2-Methyl-2-propanesulfinamide; (S)-t-Butanesulfinamide; (S)-tert-Butylsulfinamide; (S)-TBSA; (S)-2-Methyl-2-propylsulfinamide
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-Methyl-2-Propanesulfinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for asymmetric synthesis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess (ee), and other critical parameters is provided with every shipment to guarantee reproducible performance and supply chain reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.