Description

Mono-(6-(Tetraethylenepentamine)-6-Deoxy)-β-Cyclodextrin is a chemically modified cyclodextrin derivative engineered to enhance molecular encapsulation and binding affinity. This compound matters for its ability to form stable host-guest complexes, significantly improving the solubility, stability, and bioavailability of target molecules in aqueous systems. It is primarily needed by researchers and formulators in the pharmaceutical, biotechnology, and advanced material science industries for applications in drug delivery, catalysis, and analytical chemistry.

Application

• Drug Delivery Systems: As a functional excipient to solubilize and stabilize poorly water-soluble active pharmaceutical ingredients (APIs).
• Catalysis & Synthesis: Acting as a supramolecular catalyst or chiral selector in asymmetric organic synthesis and green chemistry processes.
• Analytical Chemistry: Utilized as a chiral stationary phase additive or mobile phase modifier in HPLC and capillary electrophoresis for enantiomer separation.
• Protein & Enzyme Stabilization: Enhancing the thermal and pH stability of proteins and enzymes in diagnostic kits and biocatalysis.
• Gene Delivery: As a component in non-viral vectors for complexing and delivering nucleic acids in transfection studies.
• Environmental Remediation: For the selective binding and removal of organic pollutants or heavy metal ions from wastewater.
• Material Science: Incorporation into functional polymers, hydrogels, or sensors to impart selective molecular recognition properties.
• Cosmetic Formulations: To improve the stability and controlled release of active ingredients in topical products.

Basic Information

Product Name	Mono-(6-(Tetraethylenepentamine)-6-Deoxy)-β-Cyclodextrin
CAS No.	343315-27-5
Molecular Formula	C56H100N6O34
Molecular Weight	~1449.42 g/mol
Synonyms	6A-Tetraethylenepentamino-6A-deoxy-β-cyclodextrin; 6-Tetraethylenepentamino-6-deoxy-β-cyclodextrin; β-CD-TEPA; Mono-6-deoxy-6-(tetraethylenepentamine)-β-cyclodextrin; Heptakis(6-deoxy-6-tetraethylenepentamino)-β-cyclodextrin (incorrect for mono-substituted, but a common search variant); Amino-functionalized β-Cyclodextrin; TEPA-β-CD; Cyclodextrin-polyamine conjugate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized to confirm identity, purity, and functional integrity. Certificates of Analysis (COA) are available upon request, detailing key parameters such as degree of substitution, assay, and impurity profiles. We adhere to GMP principles where applicable to support pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Degree of Substitution (NMR)	0.9 - 1.1
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.