Description

Sodium Glycocholate Hydrate is the sodium salt of the conjugated bile acid glycocholic acid. This high-purity biochemical is a critical component for research and industrial applications requiring precise biological activity and solubility. It is primarily utilized in the life sciences, pharmaceutical development, and diagnostic reagent formulation. Its consistent quality makes it an essential standard and raw material for advanced biochemical processes.

Application

• Pharmaceutical Research & Development: Used as a key reference standard and excipient in drug formulation studies, particularly for enhancing the solubility and absorption of poorly soluble active pharmaceutical ingredients (APIs).
• Diagnostic Reagent Manufacturing: Serves as a critical component in the production of clinical diagnostic kits, especially for liver function tests and enzymatic assays.
• Cell Culture & Microbiology: Employed in cell culture media as a surfactant and to facilitate membrane permeability in various in vitro studies.
• Biochemical Standardization: Acts as a primary standard for the calibration of analytical instruments and the quantification of bile acids in biological samples via HPLC or LC-MS.
• Digestive Aid Formulation: Used in the research and development of therapeutic supplements and medications aimed at supporting lipid digestion and absorption.

Basic Information

Product Name	Sodium Glycocholate Hydrate
CAS No.	338950-81-5
Molecular Formula	C26H42NNaO6 • xH2O
Molecular Weight	487.61 g/mol (anhydrous basis)
Synonyms	Glycocholic Acid Sodium Salt Hydrate; Sodium Glycocholate; N-[(3α,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]glycine Sodium Salt; Cholylglycine Sodium Salt; Tauroglycocholate (related); Sodium Cholylglycinate; GCA Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium Glycocholate Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and production use. Certificates of Analysis (COA) documenting purity, water content, and related substances are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and prevent clumping. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.