Description

Methyl-D-Erythritol Phosphate CAS NO 332888-40-1 is a key phosphorylated intermediate in the non-mevalonate (MEP/DOXP) pathway for isoprenoid biosynthesis. This compound is of significant interest for biochemical research and the development of novel antimicrobial agents targeting this essential metabolic route in bacteria and apicomplexan parasites. It serves as a critical building block for researchers and developers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Biochemical Research: Essential substrate and intermediate for studying the MEP/DOXP pathway enzyme kinetics and inhibition.
• Antimicrobial Drug Discovery: Target molecule for the development of new antibiotics and antimalarials that disrupt isoprenoid synthesis in pathogens.
• Enzyme Assay Development: Used in high-throughput screening assays to identify novel inhibitors of IspC (DXP reductoisomerase) and other pathway enzymes.
• Metabolic Pathway Analysis: A tool for isotopic labeling studies to trace metabolic flux in genetically engineered microorganisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control in related pharmaceutical development.
• Synthetic Biology: Precursor molecule in engineered biosynthetic pathways for the production of isoprenoids in microbial hosts.

Basic Information

Product Name	Methyl-D-Erythritol Phosphate
CAS No.	332888-40-1
Molecular Formula	C5H13O7P
Molecular Weight	216.12 g/mol
Synonyms	MEP; 2-C-Methyl-D-erythritol 4-phosphate; 4-(Phosphonooxy)-2-C-methyl-D-erythritol; (2R,3S)-1,3,4-Trihydroxy-3-methylbutan-2-yl dihydrogen phosphate; 2-C-Methyl-D-erythrose 4-phosphate derivative; DOXP pathway intermediate; IspC substrate
EINECS	Contact for details

Quality Control

Our Methyl-D-Erythritol Phosphate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain quality. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.