Description

16:0-18:1 Epc (Cl Salt) is a high-purity synthetic phospholipid derivative, specifically a chloride salt of a phosphatidylcholine analog with defined acyl chains. This compound is critical for advanced research and development in life sciences, offering a precisely characterized building block for creating biomimetic membranes and delivery systems. It is primarily utilized by pharmaceutical R&D teams, formulation scientists, and academic researchers working on liposomal drug delivery, diagnostic agents, and membrane biophysics studies.

Application

• Liposomal Drug Delivery Systems: As a key excipient for formulating stable, targeted liposomes for cancer therapeutics, vaccines, and nucleic acid delivery.
• Biomimetic Membrane Research: For constructing defined model membranes (e.g., vesicles, supported lipid bilayers) to study protein-lipid interactions and membrane dynamics.
• Diagnostic Agent Formulation: In the development of contrast agents for medical imaging (e.g., ultrasound, MRI) and in vitro diagnostic assays.
• Cell Culture & Biotechnology: As a supplement in specialized serum-free media or for creating lipid nanoparticles (LNPs) for gene therapy applications.
• Cosmetic & Dermal Formulations: Used in high-end cosmetic products as a skin-identical lipid to enhance barrier function and active ingredient penetration.
• Reference Standard & Analytical Use: Serves as a certified reference material for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Product Name	16:0-18:1 Epc (Cl Salt)
CAS No.	328250-19-7
Molecular Formula	C44H87NO8P • Cl
Molecular Weight	808.60 g/mol (for free base, Cl salt form varies)
Synonyms	1-Palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine chloride; Ethylphosphocholine chloride (16:0-18:1); EPC (16:0/18:1) chloride salt; 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-ethylphosphocholine chloride; PALMITOYL OLEOYL EPC CHLORIDE; Synthetic phospholipid chloride salt; Ethyl-PC (16:0-18:1) Cl; EPC Cl Salt (PO)
EINECS	Contact for details

Quality Control

Every batch of 16:0-18:1 Epc (Cl Salt) is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We ensure identity, purity, and consistency through advanced techniques including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, related substances, and residual solvents. Our quality commitment supports applications requiring GMP-grade materials for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.