Description

1-Palmitoyl(D31)-2-Oleoyl-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt) is a deuterated, high-purity phospholipid standard, specifically a sodium salt of phosphatidylserine (PS). This compound is critical for advanced analytical research and quality control, where precise quantification and tracing of lipid molecules are required. It is primarily utilized by researchers and quality assurance professionals in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as lipidomics, membrane biophysics, and metabolic studies.

Application

• Internal Standard for Lipidomics & Mass Spectrometry: Serves as a quantitative internal standard for the accurate analysis of phosphatidylserine species in complex biological samples via LC-MS/MS.
• Biophysical Research: Used in model membrane studies to investigate the role of phosphatidylserine in membrane asymmetry, protein-lipid interactions, and apoptosis signaling.
• Pharmaceutical Development: Employed in the formulation and analysis of lipid-based drug delivery systems, such as liposomes and lipid nanoparticles (LNPs).
• Diagnostic Assay Development: Acts as a critical reference material in the development of clinical assays for detecting phospholipid-related disorders or biomarkers.
• Metabolic Tracing Studies: The deuterated palmitoyl chain (D31) allows for precise tracking of lipid metabolism, synthesis, and turnover in cellular and in vivo models.
• Quality Control & Method Validation: Essential for validating analytical methods, ensuring accuracy, precision, and compliance in GLP/GMP environments for pharmaceutical and nutraceutical products containing phospholipids.

Basic Information

Product Name	1-Palmitoyl(D31)-2-Oleoyl-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt)
CAS No.	327178-96-1
Molecular Formula	C42H69D31NNaO10P
Molecular Weight	~ 888.1 g/mol (for monoisotopic mass)
Synonyms	POP-d31 PS (Sodium Salt); 16:0(d31)-18:1 PS (Sodium Salt); 1-Palmitoyl-d31-2-oleoyl-sn-glycero-3-phosphoserine (Sodium Salt); Deuterated Phosphatidylserine; PS(16:0(d31)/18:1(9Z)) (Sodium Salt); 1-Hexadecanoyl-d31-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (Sodium Salt); L-α-Phosphatidylserine (16:0(d31),18:1) (Sodium Salt)
EINECS	Contact for details

Quality Control

Our deuterated phospholipid standards are produced under stringent conditions to ensure the highest levels of isotopic purity and chemical integrity. Each batch is characterized using a combination of advanced analytical techniques including NMR, mass spectrometry, and HPLC to confirm identity, purity, and isotopic enrichment. Certificates of Analysis (COA) are provided, detailing lot-specific data for critical parameters such as chemical purity, isotopic purity (D-enrichment), and solvent content. We support compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR & MS)	Conforms to structure
Purity (HPLC)	≥ 98% (Area %)
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (TLC)	Single spot
Solvent Content (Residual Solvents)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.