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1,2-Dimyristoyl-D54-Sn-Glycero-3-[Phospho-L-Serine](Sodium Salt) CAS NO 327178-93-8


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CAS No.:327178-93-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dimyristoyl-D54-Sn-Glycero-3-[Phospho-L-Serine](Sodium Salt) is a deuterated, saturated phospholipid derivative of phosphatidylserine, a critical component of biological membranes. This high-purity, isotopically labeled compound is essential for advanced research requiring precise molecular tracking and structural analysis. It is primarily utilized by pharmaceutical researchers, biochemists, and analytical scientists in the development of lipid-based drug delivery systems, membrane biophysics studies, and as a standard in mass spectrometry.

Application

  • Deuterated Internal Standard for the quantitative analysis of phosphatidylserine and related lipids via mass spectrometry (LC-MS, GC-MS).
  • Membrane Biophysics Research for studying lipid bilayer structure, dynamics, and protein-lipid interactions using techniques like NMR and neutron scattering.
  • Lipidomics and Metabolomics as a critical reference material for accurate identification and quantification in complex biological samples.
  • Pharmaceutical R&D in the formulation and characterization of liposomal and nanoparticle-based drug delivery vehicles.
  • Biochemical Assays to investigate the role of phosphatidylserine in cellular processes such as apoptosis and signal transduction.
  • Synthetic Lipid Chemistry as a high-purity building block for the synthesis of more complex, labeled phospholipid analogs.

Basic Information

Product Name 1,2-Dimyristoyl-D54-Sn-Glycero-3-[Phospho-L-Serine](Sodium Salt)
CAS No. 327178-93-8
Molecular Formula C37D54NNaO10P
Molecular Weight ~746.9 g/mol (deuterated form)
Synonyms 1,2-Dimyristoyl-sn-glycero-3-phosphoserine (sodium salt) (d54); Deuterated DMPS (sodium salt); DMPC-d54 (sodium salt); PS(14:0/14:0)-d54 Sodium Salt; 1,2-Ditetradecanoyl-sn-glycero-3-phospho-L-serine (sodium salt) (perdeuterated); L-α-Phosphatidylserine, dimyristoyl, sodium salt (deuterated); (2R)-2-[(1,3-Dioxotetradecyl-D27)oxy]-3-[(1-oxotetradecyl-D27)oxy]propyl (2S)-2-amino-3-phosphonooxypropanoate sodium salt
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Quality Control

This high-value specialty chemical is produced under strict quality control protocols to ensure isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D, %), chemical purity, and related substance analysis is provided with every shipment to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item Specification
Appearance White to off-white solid or film
Identification (NMR) Conforms to structure
Isotopic Purity (D) ≥ 98 atom % D
Chemical Purity (HPLC) ≥ 95%
Assay ≥ 95% (by phosphorus analysis)
Solubility Soluble in chloroform, methanol, ethanol; forms dispersions in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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