Description

1-Oleoyl-2-Hydroxy-Sn-Glycero-3[Phospho-L-Serine](Sodium Salt) is a high-purity, synthetic lysophospholipid, specifically a lysophosphatidylserine (lyso-PS) derivative. This compound is a critical biochemical tool and a key intermediate in lipid research and development. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors. Its defined structure enables precise studies of lipid signaling, membrane biophysics, and the development of lipid-based drug delivery systems.

Application

• Biochemical Research: As a standard and substrate for studying phospholipase A2 (PLA2) activity, lipid metabolism, and cell signaling pathways involving phosphatidylserine receptors.
• Pharmaceutical Development: A key intermediate in the synthesis of more complex phospholipids for use in liposomal drug formulations and targeted delivery systems.
• Cell Biology & Neuroscience: Used in studies of apoptosis (programmed cell death), where externalized phosphatidylserine acts as an "eat-me" signal, and in research on synaptic function.
• Cosmetic & Dermocosmetic Formulations: Incorporated into advanced skincare products for its potential role in supporting skin barrier function and cellular signaling.
• Lipidomics & Analytical Standards: Serves as a critical reference standard for mass spectrometry-based lipidomic analysis to identify and quantify lipid species in biological samples.
• Biomimetic Membrane Models: Used to create simplified membrane systems (e.g., vesicles, monolayers) to investigate lipid-protein interactions and membrane dynamics.

Basic Information

Product Name	1-Oleoyl-2-Hydroxy-Sn-Glycero-3[Phospho-L-Serine](Sodium Salt)
CAS No.	326589-90-6
Molecular Formula	C27H51NNaO10P
Molecular Weight	603.66 g/mol
Synonyms	1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoserine (sodium salt); Lyso-PS(18:1); Lysophosphatidylserine (18:1); 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium salt; (2R)-2-Hydroxy-3-[(1Z)-octadec-1-en-1-yloxy]propyl (2S)-2-amino-3-phosphonooxypropanoate sodium salt; Oleoyl lysophosphatidylserine; LysoPS; LPS (18:1/0:0) sodium salt
EINECS	Contact for details

Quality Control

Our 1-Oleoyl-2-Hydroxy-Sn-Glycero-3[Phospho-L-Serine](Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.