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1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) CAS NO 326495-22-1
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CAS No.:326495-22-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is a high-purity, synthetic lysophospholipid, specifically a sodium salt of a lysophosphatidylglycerol (LPG) analog. This compound serves as a critical research-grade biochemical and a versatile lipid building block for advanced formulation development. It is essential for scientists and manufacturers in pharmaceutical R&D, lipidomics, and advanced drug delivery systems, particularly for studying membrane biophysics and creating lipid-based nanoparticles.
Application
- Lipidomics Research & Biomarker Discovery: Used as a standard or an internal standard in mass spectrometry for the identification and quantification of lysophospholipids in biological samples.
- Pharmaceutical R&D (Drug Delivery): A key excipient and structural component in the development of liposomes, niosomes, and other lipid nanoparticle (LNP) formulations for targeted drug and gene delivery.
- Biochemical & Cell Biology Studies: Employed to investigate the role of lysophosphatidylglycerols in cell signaling, membrane dynamics, and inflammation pathways.
- Cosmetic & Dermal Formulations: Incorporated into high-end skincare products for its potential emulsifying and skin-barrier enhancing properties.
- Synthetic Lipid Chemistry: Serves as a precursor or intermediate for the chemical synthesis of more complex, tailored phospholipids and lipid conjugates.
- Membrane Protein Research: Used in the reconstitution and stabilization of membrane proteins for structural and functional analysis.
Basic Information
| Product Name | 1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) |
| CAS No. | 326495-22-1 |
| Molecular Formula | C22H44NaO9P |
| Molecular Weight | 506.54 g/mol |
| Synonyms | LPG (16:0); 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphoglycerol sodium salt; Lysophosphatidylglycerol (16:0) sodium salt; 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; rac-1-(1-Hexadecanoyloxy)-3-(phosphonooxy)-2-propanol hydrogen sodium salt; Sodium 1-palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol); LysoPG(16:0/0:0) sodium salt |
| EINECS | Contact for details |
Quality Control
Every batch of our 1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality system is designed to meet the stringent requirements of research and development applications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 95.0% |
| Related Substances (HPLC) | Total impurities ≤ 5.0% |
| Water Content (KF) | ≤ 5.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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