Description

Heptadecanoyl Coenzyme A (Lithium Salt) is a high-purity, chemically defined long-chain acyl-CoA ester, a critical biochemical intermediate in lipid metabolism research. This compound is essential for studying enzyme kinetics, substrate specificity, and metabolic pathways involving fatty acid activation and β-oxidation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for target validation, assay development, and the production of diagnostic reagents.

Application

• Enzymology Research: Serves as a specific substrate for studying acyl-CoA synthetases, thioesterases, and other enzymes involved in lipid metabolism.
• Metabolic Pathway Analysis: Used in in vitro assays to investigate fatty acid β-oxidation, lipid biosynthesis, and related cellular processes.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) campaigns to identify and characterize novel inhibitors or activators of metabolic enzymes as potential drug targets.
• Diagnostic Reagent Manufacturing: Acts as a key raw material in formulating enzymatic test kits for clinical diagnostics and research use.
• Biochemical Standard: Provides a calibrated reference standard for quantitative analysis via LC-MS, HPLC, or other analytical techniques.
• Cell Biology Studies: Utilized to probe the role of specific acyl-CoA molecules in cellular signaling, membrane dynamics, and energy homeostasis.

Basic Information

Product Name	Heptadecanoyl Coenzyme A (Lithium Salt)
CAS No.	324766-64-5
Molecular Formula	C38H66N7O17P3S • xLi
Molecular Weight	~1057.9 g/mol (Free acid, approximate)
Synonyms	Heptadecanoyl-CoA (Lithium Salt); C17:0-CoA; Margaroyl Coenzyme A (Lithium Salt); Coenzyme A, S-heptadecanoate; Heptadecanoyl-Coenzyme A Lithium; 3'-Phosphoadenosine 5'-(3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(1-oxoheptadecyl)sulfanyl]ethyl})amino)propyl]amino}butyl] dihydrogen diphosphate), Lithium Salt; S-Heptadecanoylcoenzyme A Lithium Salt
EINECS	Contact for details

Quality Control

Our Heptadecanoyl Coenzyme A (Lithium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and/or MS), and other critical parameters are provided and available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO (limited)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.