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1-Palmitoyl-2-(6,7-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine CAS NO 324054-50-4


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CAS No.:324054-50-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Palmitoyl-2-(6,7-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid derivative, specifically a brominated phosphatidylcholine. This compound is of significant value as a specialized biochemical tool and a critical building block for advanced lipid research and formulation. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications requiring precisely engineered lipid structures.

Application

  • Biophysical Research: As a key component in model membrane systems (e.g., liposomes, bilayers) to study membrane fluidity, protein-lipid interactions, and the effects of halogenated lipids on biophysical properties.
  • Drug Delivery Development: Used in the formulation of specialized liposomal carriers where the bromine atoms can serve as sites for further chemical conjugation or to modulate stability and release profiles.
  • Pharmaceutical Intermediates: Serves as a critical synthetic intermediate for the production of more complex, target-specific phospholipid-based active pharmaceutical ingredients (APIs) or prodrugs.
  • Bioconjugation & Labeling: The bromine functional groups provide handles for site-specific bioconjugation reactions, enabling the attachment of fluorescent probes, targeting ligands, or other molecules.
  • Standards & Reference Materials: Employed as a certified reference standard in analytical laboratories for lipidomics, quality control of lipid-based products, and method validation.
  • Specialty Surfactants: Potential use in high-value industrial applications requiring surfactants with unique steric and electronic properties derived from the brominated acyl chain.

Basic Information

Product Name 1-Palmitoyl-2-(6,7-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine
CAS No. 324054-50-4
Molecular Formula C42H82Br2NO8P
Molecular Weight 912.89 g/mol
Synonyms 6,7-Dibromo-PSPC; 1-Palmitoyl-2-(6,7-dibromostearoyl)-sn-glycero-3-phosphocholine; Brominated Phosphatidylcholine; PC(16:0/18:0(6,7-Br2)); Dibromostearoyl Phosphocholine; (6,7-Dibromo)stearoyl-PC; 1-Hexadecanoyl-2-[(6,7-dibromooctadecanoyl)]-sn-glycero-3-phosphocholine
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Quality Control

Our 1-Palmitoyl-2-(6,7-Dibromo)Stearoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Assay (NMR) ≥ 90% (w/w)
Water Content (KF) ≤ 2.0 %
Solvent Residues (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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