Description

1,2-Dilinoleoyl-Sn-Glycero-3-Phosphate (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a sodium salt of phosphatidic acid with linoleic acid chains. This compound is a critical building block in advanced lipid-based formulations, offering superior emulsifying and membrane-mimicking properties. It is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced material sectors developing liposomal drug delivery systems, lipid nanoparticles (LNPs), and sophisticated cosmetic actives.

Application

• Liposomal & Lipid Nanoparticle (LNP) Formulations: A key structural phospholipid for constructing stable vesicles for mRNA, siRNA, and small molecule drug delivery.
• Biomembrane & Cell Biology Research: Used to create model membranes for studying lipid-protein interactions, membrane fusion, and permeability.
• Cosmetic & Dermal Delivery Systems: Acts as a high-performance emulsifier and penetration enhancer in premium skincare products for targeted active delivery.
• Nutraceutical Encapsulation: Employed to encapsulate sensitive bioactive compounds like ω-3 fatty acids or vitamins to improve stability and bioavailability.
• Biomaterial & Medical Device Coatings: Provides a biocompatible, non-thrombogenic surface coating for implants and diagnostic devices.
• Analytical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in lipidomics.

Basic Information

Product Name	1,2-Dilinoleoyl-Sn-Glycero-3-Phosphate (Sodium Salt)
CAS No.	322647-62-1
Molecular Formula	C39H67NaO8P
Molecular Weight	717.90 g/mol
Synonyms	Sodium 1,2-Dilinoleoyl-sn-glycero-3-phosphate; PA(18:2/18:2) Sodium Salt; 1,2-Di-Linoleoyl Phosphatidic Acid Sodium Salt; Phosphatidic Acid (18:2/18:2) Sodium Salt; sn-Glycero-3-phosphoric Acid Sodium Salt (1,2-Dilinoleoyl Ester); DLPA Sodium Salt; (2R)-2,3-Bis[[(9Z,12Z)-octadeca-9,12-dienoyl]oxy]propyl Sodium Phosphate
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Dilinoleoyl-Sn-Glycero-3-Phosphate (Sodium Salt) is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and MS. Our production adheres to cGMP guidelines where applicable, supporting its use in pharmaceutical R&D and pre-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. For long-term storage, desiccate to protect against moisture. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Linoleic Acid Content	≥ 98.0% of total fatty acids
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.