Description

1,2-Dielaidoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a sodium salt of phosphatidylglycerol with defined trans-unsaturated fatty acid chains. This compound is critical for advanced research and formulation development where precise lipid composition and stereochemistry are paramount. It serves as an essential building block for researchers and product developers in the pharmaceutical, biotechnology, and advanced material science sectors, enabling the creation of sophisticated lipid-based delivery systems and model membranes.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key component for constructing stable, anionic liposomal bilayers used in drug delivery, mRNA vaccines, and diagnostic agents.
• Biomimetic Membrane Research: Used to create defined model membranes for studying protein-lipid interactions, membrane fusion, and permeability.
• Pulmonary Surfactant Mimetics: Investigated as a synthetic component in therapeutic surfactants for respiratory distress syndrome due to its anionic headgroup properties.
• Drug Encapsulation & Targeting: Enhances the encapsulation efficiency and stability of charged therapeutic molecules and can influence biodistribution profiles.
• Biophysical Studies: Essential for calorimetry (DSC), spectroscopy, and scattering experiments to understand phase behavior and thermodynamics of lipid assemblies.
• Cosmetic & Dermal Formulations: Incorporated into advanced cosmetic products as a biocompatible emulsifier and skin-conditioning agent.

Basic Information

Product Name	1,2-Dielaidoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt)
CAS No.	322647-40-5
Molecular Formula	C44H80NaO10P
Molecular Weight	823.06 g/mol
Synonyms	1,2-Dielaidoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; PG(18:1(9E)/18:1(9E)) sodium salt; (9E,9'E)-1,2-Dioctadec-9-enoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; Sodium 1,2-dielaidoyl-sn-glycero-3-phospho-(1'-rac-glycerol); trans-Phosphatidylglycerol sodium salt; 1,2-Di-(9E-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; Anionic Phospholipid Sodium Salt; Dielaidoyl PG Sodium Salt
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Dielaidoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR, HPLC, and MS to verify chemical identity, isomeric purity, and lipid composition. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and critical impurity profiles is provided with each shipment to ensure it meets the exacting standards required for research and GMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Phosphorus)	≥ 98.0%
Fatty Acid Composition	≥ 95% Elaidic Acid (C18:1 trans-9)
Solubility	Soluble in chloroform, methanol; forms dispersions in water
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.