Description

1,2-Didecanoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is a high-purity synthetic phospholipid, specifically a sodium salt of a phosphatidylglycerol derivative with defined decanoyl (C10:0) fatty acid chains. This compound is critical for creating well-defined, reproducible model membrane systems essential for biophysical research and pharmaceutical development. It is primarily utilized by researchers and formulators in the life sciences sector for studying membrane biophysics, developing advanced drug delivery systems such as liposomes, and as a key component in diagnostic assays.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: Serves as a structurally defined component for creating stable, uniform liposomal carriers for drug delivery, including mRNA vaccines and cancer therapeutics.
• Biophysical Membrane Research: Used to construct controlled model lipid bilayers (e.g., vesicles, supported bilayers) for studying protein-lipid interactions, membrane permeability, and fusion mechanisms.
• Diagnostic Reagent Development: Acts as a substrate or a stabilizing agent in enzymatic assays and immunoassays that involve lipid membranes or phospholipid-dependent processes.
• Biomimetic Coatings: Employed to create biocompatible, non-fouling surfaces on medical devices and sensors by mimicking natural cell membrane properties.
• Cell Culture & Transfection: Used as an additive in specialized cell culture media or as a component in non-viral transfection reagents to enhance DNA/RNA delivery into cells.
• Reference Standard: Provides a high-purity analytical standard for quality control in the production of phospholipid-based pharmaceuticals and reagents.

Basic Information

Product Name	1,2-Didecanoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt)
CAS No.	322647-25-6
Molecular Formula	C26H50NaO10P
Molecular Weight	576.64 g/mol
Synonyms	1,2-Didecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; PG(10:0/10:0) sodium salt; 1,2-Di-O-decanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; Didecanoyl Phosphatidylglycerol Sodium Salt; Sodium 1,2-didecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol); 1,2-Di-C10:0 PG (Na); Phosphatidylglycerol (10:0/10:0) sodium salt; rac-1,2-Didecanoyl-glycero-3-phosphoglycerol sodium salt
EINECS	Contact for details

Quality Control

Our 1,2-Didecanoyl-Sn-Glycero-3-Phospho-(1'-Rac-Glycerol) (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.