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1-Steraoyl-2-Linoleoyl-Sn-Glycero-3-Phospho-L-Serine (Monosodium Salt) CAS NO 322647-11-0


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CAS No.:322647-11-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Stearoyl-2-Linoleoyl-sn-Glycero-3-Phospho-L-Serine (Monosodium Salt) is a high-purity, synthetic phosphatidylserine (PS) species, a critical phospholipid component of biological membranes. This compound is essential for advanced research and development in lipidomics, membrane biophysics, and the formulation of lipid-based delivery systems. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of high-end nutraceuticals and liposomal products.

Application

  • Lipidomics Research & Biomarker Discovery: Used as a standard reference material for the identification and quantification of phosphatidylserine species in complex biological samples via mass spectrometry.
  • Membrane Biophysics Studies: Essential for constructing model lipid bilayers and vesicles to study membrane asymmetry, protein-lipid interactions, and apoptosis signaling.
  • Liposomal Drug Delivery Systems: A key functional excipient for formulating targeted liposomes, enhancing drug loading efficiency and influencing cellular uptake mechanisms.
  • Cell Culture & Neuroscience Research: Employed in serum-free media supplements and studies focused on neuronal cell health, synaptic function, and cognitive support pathways.
  • Pharmaceutical Reference Standard: Serves as a certified reference material for quality control and regulatory filing of phospholipid-based therapeutics and diagnostics.
  • Advanced Nutraceutical Formulations: A premium ingredient for clinical-grade dietary supplements targeting cognitive health and stress response.

Basic Information

Product Name 1-Stearoyl-2-Linoleoyl-sn-Glycero-3-Phospho-L-Serine (Monosodium Salt)
CAS No. 322647-11-0
Molecular Formula C46H85NNaO10P
Molecular Weight 866.14 g/mol
Synonyms 18:0-18:2 PS (Sodium Salt); PS(18:0/18:2(9Z,12Z)); 1-Octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine (Sodium Salt); L-α-Phosphatidylserine (18:0-18:2); Sodium 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphoserine; Phosphatidylserine (Stearoyl, Linoleoyl); SLPS; (3-sn-Phosphatidyl)-L-serine, sodium salt
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Quality Control

Our 1-Stearoyl-2-Linoleoyl-sn-Glycero-3-Phospho-L-Serine (Monosodium Salt) is manufactured under strict quality systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and traceable to primary standards. Production adheres to cGMP guidelines for pharmaceutical-grade raw materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and light-sensitive nature. For long-term storage, desiccate. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/MS) Conforms
Identification (NMR) Conforms
Purity (HPLC, Area%) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals < 10 ppm
Microbial Limits < 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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