Description

1,2-Didecanoyl-Sn-Glycero-3-Phosphate (Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a phosphatidic acid analogue with defined acyl chains. This compound matters as a critical biochemical tool and a versatile building block for advanced lipid research and formulation development. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetics industries for applications such as liposome preparation, membrane biophysics studies, and as a precursor for more complex lipids.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: Serves as a key component or structural modifier in the creation of drug delivery vesicles for mRNA, siRNA, and other therapeutic agents.
• Biochemical Research: Used as a substrate or standard in enzymatic assays involving phospholipases, lipid kinases, and phosphatases to study lipid metabolism and signaling pathways.
• Membrane Biophysics: Employed in model membrane systems (e.g., vesicles, bilayers) to investigate membrane fluidity, phase behavior, and protein-lipid interactions.
• Cosmetic Actives: Functions as a bioactive ingredient or emulsifier in high-end skincare formulations for its potential skin-barrier repair and moisturizing properties.
• Pharmaceutical Intermediates: Acts as a synthetic precursor for the production of more complex phospholipids like phosphatidylglycerol or cardiolipin analogs.
• Analytical Standards: Provides a high-purity reference standard for lipidomic analysis using techniques such as LC-MS or HPLC.

Basic Information

Product Name	1,2-Didecanoyl-Sn-Glycero-3-Phosphate (Sodium Salt)
CAS No.	321883-64-1
Molecular Formula	C23H44NaO8P
Molecular Weight	502.56 g/mol
Synonyms	1,2-Didecanoyl-sn-glycerol-3-phosphate sodium salt; PA(10:0/10:0) sodium salt; Phosphatidic Acid(20:0) sodium salt; 1,2-Dicapryloyl-sn-glycero-3-phosphate sodium salt; Decanoic acid, 1-[(1-oxodecyl)oxy]-3-(phosphonooxy)-2-propyl ester, sodium salt (1:1); sn-Glycero-3-phosphoric acid 1,2-didecanoate sodium salt; L-α-Phosphatidic acid, didecanoyl-, sodium salt
EINECS	Contact for details

Quality Control

Our 1,2-Didecanoyl-Sn-Glycero-3-Phosphate (Sodium Salt) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting research and cGMP-grade applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.