Description

1,2-Dilinoleoyl-Sn-Glycero-3-[Phospho-L-Serine](Sodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylserine (PS) species with linoleic acid chains. This compound is critical for advanced research and formulation in life sciences due to its role as a key component of cell membranes and its involvement in cellular signaling processes. It is essential for pharmaceutical developers, academic researchers, and manufacturers of advanced lipid-based delivery systems such as liposomes and lipid nanoparticles (LNPs).

Application

• Pharmaceutical Research & Drug Delivery: A critical raw material for formulating liposomes and lipid nanoparticles (LNPs) used in mRNA vaccines, cancer therapeutics, and other targeted drug delivery systems.
• Biochemical & Cell Biology Research: Used in studies of apoptosis (programmed cell death), membrane asymmetry, and intracellular signaling pathways as a component of model membranes.
• Nutraceutical & Cosmetic Formulations: Incorporated into high-end dietary supplements for cognitive health and premium cosmetic products for skin barrier repair and anti-aging benefits.
• Diagnostic Reagent Production: Serves as a component in diagnostic kits and assays that detect antibodies or study membrane-protein interactions.
• Excipient for Advanced Therapies: Potential use as an excipient in complex injectable formulations, where its biocompatibility and functional properties are leveraged.

Basic Information

Product Name	1,2-Dilinoleoyl-Sn-Glycero-3-[Phospho-L-Serine](Sodium Salt)
CAS No.	321883-39-0
Molecular Formula	C45H78NO10PNa
Molecular Weight	846.07 g/mol
Synonyms	PS(18:2/18:2); 1,2-DiLinoleoyl-sn-glycero-3-phospho-L-serine sodium salt; L-α-Phosphatidylserine (Sodium Salt) from Soybean (Linoleic Acid-rich); Sodium 1,2-Dilinoleoyl-sn-glycero-3-phosphoserine; Phosphatidylserine (18:2 PS); DOPS (DiOleoyl PhosphatidylSerine) variant; (2S)-2,3-Bis[[(9Z,12Z)-octadeca-9,12-dienoyl]oxy]propyl (2S)-2-amino-3-phosphonooxypropanoate sodium salt
EINECS	Contact for details

Quality Control

Our 1,2-Dilinoleoyl-Sn-Glycero-3-[Phospho-L-Serine](Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized. For short-term use, vials may be stored at 2-8°C, but repeated freeze-thaw cycles should be avoided. Keep the container tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.