Description

1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt) is a high-purity, synthetic phosphatidylserine (PS) lipid, a critical component of biological membranes. This compound is essential for research and development in advanced life sciences, particularly in the study of cell signaling, apoptosis, and membrane biophysics. It is primarily utilized by pharmaceutical researchers, diagnostic developers, and manufacturers of lipid-based drug delivery systems such as liposomes and lipid nanoparticles (LNPs).

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key phospholipid component for constructing stable, biocompatible vesicles for drug and gene delivery.
• Cell Biology & Biochemistry Research: Used to study membrane asymmetry, cell signaling pathways, and apoptotic processes in vitro.
• Diagnostic Reagent Development: Serves as a critical raw material in the production of test kits and assays for clinical diagnostics.
• Neuroscience Research: Investigated for its role in cognitive function and neuronal membrane maintenance.
• Biomimetic Membrane Models: Employed in creating artificial membrane systems for studying protein-lipid interactions.
• Pharmaceutical Excipient: Potential functional excipient in advanced parenteral formulations.

Basic Information

Product Name	1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt)
CAS No.	321863-21-2
Molecular Formula	C42H78NO10PNa
Molecular Weight	810.03 g/mol
Synonyms	POPS; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoserine (sodium salt); Phosphatidylserine (16:0-18:1); PS (16:0-18:1); (2S)-2-Amino-3-({[(2R)-2,3-bis(hexadecanoyloxy)propoxy](hydroxy)phosphoryl}oxy)propanoic acid sodium salt; L-α-Phosphatidylserine, 1-palmitoyl-2-oleoyl-, sodium salt; 1-Palmitoyl-2-oleoylphosphatidylserine
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-[Phospho-L-Serine] (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol, ethanol; forms dispersions in water
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.