Description

1,2-Distearoyl-Sn-Glycero-3-Phospho-L-Serine Sodium Salt is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylserine (PS) species with saturated stearoyl chains. This compound is critical for its role as a key building block in the formulation of advanced lipid-based delivery systems and biomimetic membranes. It is primarily required by pharmaceutical, biotechnology, and advanced cosmetic research sectors for developing liposomal drug carriers, diagnostic agents, and high-performance skincare formulations.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A critical excipient for constructing stable, anionic liposomal bilayers used in drug delivery for cancer therapeutics, vaccines, and nucleic acid (e.g., mRNA) encapsulation.
• Biomimetic Membrane Research: Used in model membrane systems (e.g., vesicles, supported lipid bilayers) to study cell signaling, apoptosis, and protein-lipid interactions due to its role in cellular processes.
• Pharmaceutical & Cosmetic Actives Carrier: Enhances the stability and skin penetration of active ingredients in premium cosmetic and dermatological products.
• Diagnostic Agent Development: Serves as a component in contrast agents or probes for medical imaging techniques like MRI and ultrasound.
• Cell Culture & Biochemistry: Used as a supplement in serum-free media or as a substrate for enzymatic studies involving phospholipases.
• Neuroscience Research: Investigated for its neuroprotective properties and role in cognitive function in supplement and nutraceutical research contexts.

Basic Information

Product Name	1,2-Distearoyl-Sn-Glycero-3-Phospho-L-Serine Sodium Salt
CAS No.	321595-13-5
Molecular Formula	C42H81NNaO10P
Molecular Weight	814.06 g/mol
Synonyms	DSPS; 1,2-Distearoyl-sn-glycero-3-phosphoserine sodium salt; Distearoylphosphatidylserine sodium salt; Phosphatidylserine (18:0/18:0) sodium salt; L-α-Phosphatidylserine (distearoyl, sodium salt); PS(18:0/18:0); Sodium 1,2-distearoyl-sn-glycero-3-phospho-L-serinate; 1,2-Di-O-octadecanoyl-sn-glycero-3-phospho-L-serine sodium salt
EINECS	Contact for details

Quality Control

Our 1,2-Distearoyl-Sn-Glycero-3-Phospho-L-Serine Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to warm to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, slightly soluble in ethanol, insoluble in water
Loss on Drying	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.