Description

Tetracycline 10-o-B-D-Galactopyranoside CAS NO 319426-63-6 is a chemically modified derivative of the classic broad-spectrum antibiotic tetracycline, where a galactopyranosyl moiety is attached at the 10-position. This structural modification is designed to alter the compound's pharmacokinetic properties, solubility, and potentially its target specificity, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by research scientists and process chemists in the pharmaceutical and biotechnology sectors for the synthesis of novel antibiotic conjugates, prodrug development, and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel tetracycline-based antibiotic conjugates and targeted drug delivery systems.
• Prodrug Development: Used in research to create glycosylated prodrugs aimed at improving bioavailability, tissue targeting, or reducing side effects.
• Medicinal Chemistry Research: Essential for Structure-Activity Relationship (SAR) studies to explore new antibacterial agents and overcome bacterial resistance mechanisms.
• Biochemical Tool Compound: Serves as a specialized reagent in microbiological and enzymatic studies to investigate bacterial protein synthesis inhibition.
• API Synthesis: Intermediate in the custom synthesis of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trial materials.

Basic Information

Item	Details
Product Name	Tetracycline 10-o-B-D-Galactopyranoside
CAS No.	319426-63-6
Molecular Formula	C34H43N3O16
Molecular Weight	749.72 g/mol
Synonyms	10-O-β-D-Galactopyranosyl Tetracycline; Tetracycline 10-O-β-D-Galactoside; 10-Galactosyl Tetracycline; 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(β-D-galactopyranosyloxy)-2-naphthacenecarboxamide; Galactosylated Tetracycline Derivative; Tetracycline Galactopyranoside Ester
EINECS	Contact for details

Quality Control

Our Tetracycline 10-o-B-D-Galactopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.