Description

Fmoc-Leu-Phe-Gly-Oh CAS NO 313694-76-7 is a protected tripeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for drug discovery, development of therapeutic peptides, and biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of longer, more complex peptide chains in automated synthesizers.
• Pharmaceutical Research & Development: Used in the discovery and development of novel therapeutic peptide candidates targeting various diseases.
• Bioconjugation & Peptide Labeling: Serves as a precursor for creating peptide conjugates with dyes, tags, or other functional molecules for diagnostic and research applications.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Biochemical & Structure-Activity Relationship (SAR) Studies: Used to investigate the role of specific amino acid sequences in protein function and interaction.
• Custom Peptide Service Providers: A critical raw material for CROs and CDMOs offering bespoke peptide synthesis services to clients worldwide.

Basic Information

Product Name	Fmoc-Leu-Phe-Gly-Oh
CAS No.	313694-76-7
Molecular Formula	C33H37N3O6
Molecular Weight	571.67 g/mol
Synonyms	Fmoc-Leu-Phe-Gly-OH; Fmoc-L-F-G-OH; N-(9-Fluorenylmethoxycarbonyl)-L-leucyl-L-phenylalanylglycine; (9H-Fluoren-9-yl)methyl (2S)-2-[[(2S)-2-[[2-[(2S)-2-[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]acetate; Fmoc-Leu-Phe-Gly; Fmoc-LFG; Fmoc-L-F-G; N-Fmoc-L-leucyl-L-phenylalanylglycine
EINECS	Contact for details

Quality Control

Our Fmoc-Leu-Phe-Gly-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer-specific requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.