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Geranylgeranyl Pyrophosphate Triammonium Salt CAS NO 313263-08-0


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CAS No.:313263-08-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Geranylgeranyl Pyrophosphate Triammonium Salt is a high-purity, water-soluble ammonium salt of the essential isoprenoid intermediate geranylgeranyl pyrophosphate (GGPP). This compound serves as a critical biochemical substrate for protein prenylation and the biosynthesis of carotenoids, chlorophylls, tocopherols, and other vital terpenoids. It is indispensable for researchers and manufacturers in pharmaceutical development, plant biology, and nutraceutical production, where precise enzymatic activity and metabolic pathway studies are required.

Application

  • Enzymatic Research Substrate: Essential for in vitro studies of protein geranylgeranyltransferases (GGTases) involved in cancer and cardiovascular disease research.
  • Plant Biochemistry & Agriculture: Used to study and manipulate biosynthetic pathways for carotenoids, gibberellins, and chlorophyll in crops.
  • Pharmaceutical Development: A key reagent in screening and developing inhibitors for prenylation-dependent diseases, including certain cancers and parasitic infections.
  • Nutraceutical Synthesis: Acts as a precursor in the enzymatic synthesis of high-value compounds like coenzyme Q10 and vitamin K2.
  • Metabolic Pathway Analysis: Utilized in tracer studies and metabolic flux analysis to understand isoprenoid biosynthesis.
  • Biocatalyst & Enzyme Characterization: Serves as a standard substrate for characterizing the activity and kinetics of terpene synthases and prenyltransferases.

Basic Information

Product Name Geranylgeranyl Pyrophosphate Triammonium Salt
CAS No. 313263-08-0
Molecular Formula C20H40N3O7P2
Molecular Weight 511.49 g/mol
Synonyms GGPP Triammonium Salt; (all-E)-Geranylgeranyl Diphosphate Triammonium Salt; Geranylgeranyl Diphosphate Triammonium; Farnesyl-PP Triammonium Salt (common misnomer); (2E,6E,10E)-Geranylgeranyl Pyrophosphate Triammonium; Triammonium (2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraene-1-yl diphosphate; GGPP-(NH4)3; All-trans-Geranylgeranyl Pyrophosphate Triammonium Salt
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Quality Control

Our Geranylgeranyl Pyrophosphate Triammonium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize condensation.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Water Content (KF) ≤ 5.0 %
Solubility Soluble in water, buffer solutions
Biological Activity Tested as substrate for GGTase-I

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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