Description

Cinchonine Monohydrochloride Hydrate is a high-purity alkaloid salt derivative of cinchonine, a key chiral compound. This material is essential for its role as a versatile chiral selector and resolving agent in asymmetric synthesis and analytical chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, fine chemical, and catalyst development sectors for creating enantiomerically pure substances.

Application

• Chiral Resolution Agent: Used for the separation of enantiomers in racemic mixtures via diastereomeric salt formation.
• Asymmetric Synthesis Catalyst: Serves as a precursor or ligand in catalytic systems for stereoselective chemical reactions.
• Analytical Chemistry Standard: Employed as a reference standard in HPLC and other chromatographic methods for method development and validation.
• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and other bioactive alkaloid derivatives.
• Research & Development: Utilized in academic and industrial R&D for studying chiral recognition mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	Cinchonine Monohydrochloride Hydrate
CAS No.	312695-48-0
Molecular Formula	C19H22N2O · HCl · xH2O
Molecular Weight	344.86 (anhydrous base) + 36.46 (HCl) + (18.02*x)
Synonyms	Cinchonine Hydrochloride Hydrate; (8α,9R)-Cinchonan-9-ol Hydrochloride Hydrate; Cinchonine HCl Hydrate; Cinchonine Hydrochloride Monohydrate; Cinchonan-9-ol, hydrochloride, hydrate, (8α,9R)-; Cinchonine HCl; Cinchonine Chloride Hydrate
EINECS	Contact for details

Quality Control

Our Cinchonine Monohydrochloride Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	As per COA (Hydrate form)
Specific Rotation	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.