Description

Taurocholic Acid Sodium Salt Hydrate is a high-purity conjugated bile acid salt, essential for its role as a biological detergent and signaling molecule. This compound is critical for facilitating the solubilization and absorption of lipids and fat-soluble vitamins in biological systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from cell culture and drug delivery to biochemical research and diagnostic reagent formulation.

Application

• Pharmaceutical Research & Development: Used as a key excipient in drug formulation to enhance the solubility and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs).
• Cell Culture & Biotechnology: Serves as a critical component in mammalian cell culture media, particularly for hepatocyte studies and in vitro toxicology assays.
• Biochemical Reagents: Employed in the preparation of diagnostic kits and as a standard in analytical methods like HPLC for bile acid analysis.
• Membrane Protein Studies: Acts as a mild, effective detergent for the solubilization and stabilization of membrane proteins during purification processes.
• Lipid & Metabolic Research: Fundamental for studying bile acid metabolism, liver function, and disorders related to cholesterol homeostasis.
• Drug Delivery Systems: Incorporated into liposomal and micellar formulations to improve drug targeting and release profiles.

Basic Information

Product Name	Taurocholic Acid Sodium Salt Hydrate
CAS No.	312693-83-7
Molecular Formula	C26H44NNaO7S · xH2O
Molecular Weight	Anhydrous: 537.68 g/mol
Synonyms	Sodium Taurocholate Hydrate; Taurocholate Sodium Salt; N-Choloyltaurine Sodium Salt; 2-[(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)amino]ethanesulfonate Sodium Salt; Taurocholic Acid Sodium; Cholyltaurine Sodium Salt; Taurocholsaeure Natriumsalz
EINECS	Contact for details

Quality Control

Our Taurocholic Acid Sodium Salt Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and pharmaceutical applications. Certificates of Analysis (COA) detailing the results for purity (by HPLC), water content, residue on ignition, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.