Description

18-Methoxycoronaridine is a semi-synthetic iboga alkaloid derivative of significant interest in pharmaceutical research. This compound matters as a key intermediate and reference standard for the development of novel therapeutic agents targeting neurological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in neuroscience, addiction medicine, and neuropharmacology studies. The product is supplied with full analytical documentation to support critical R&D and quality control workflows.

Application

• Pharmaceutical Research & Development: Serves as a crucial intermediate in the synthesis of novel neuroactive compounds and potential therapeutics.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in laboratory settings.
• Neuroscience Studies: Employed in preclinical research to investigate mechanisms related to addiction, depression, and other central nervous system disorders.
• Biochemical Assays: Utilized as a ligand or substrate in receptor binding studies and enzymatic assays to explore specific biological interactions.
• Academic Research: Supports chemical and pharmacological studies in university and institutional laboratories worldwide.
• Process Chemistry: Acts as a building block for the scale-up and optimization of synthetic routes for related alkaloid derivatives.

Basic Information

Product Name	18-Methoxycoronaridine
CAS No.	308123-60-6
Molecular Formula	C22H28N2O3
Molecular Weight	368.47 g/mol
Synonyms	18-MC; 18-Methoxycoronaridine Hydrochloride (salt form); 18-Methoxycoronaridine HBr; 18-Methoxycoronaridine free base; 18-Methoxy-ibogamine; Coronaridine, 18-methoxy-; 18-Methoxy-ibogaine analog
EINECS	Contact for details

Quality Control

Our 18-Methoxycoronaridine is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling using advanced techniques like HPLC and mass spectrometry. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider keeping the material under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.