Description

1-Palmitoyl-2-Oleyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt is a high-purity, synthetic phospholipid, specifically a sodium salt of POPG (1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)). This compound is a critical component for constructing biomimetic membranes and serves as a vital raw material in advanced pharmaceutical and biotechnological research. It is essential for researchers and manufacturers in the fields of liposome formulation, drug delivery systems, and membrane biophysics studies, where precise lipid composition dictates performance and efficacy.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key excipient for creating stable, uniform vesicles for drug and gene delivery.
• Biomimetic Membrane Models: Used in research to create artificial cell membranes for studying protein-lipid interactions and membrane dynamics.
• Pharmaceutical Research: Employed in the development of injectable formulations, including mRNA vaccines and cancer therapeutics.
• Cell Culture & Biochemistry: Acts as a supplement in serum-free media or as a substrate for enzymatic studies involving phospholipases.
• Diagnostic Reagents: Utilized in the production of calibrators and controls for clinical diagnostic assays.
• Cosmetic Actives Delivery: Incorporated into advanced cosmetic formulations for enhanced skin penetration of active ingredients.

Basic Information

Product Name	1-Palmitoyl-2-Oleyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt
CAS No.	300733-65-7
Molecular Formula	C41H78NaO10P
Molecular Weight	785.02 g/mol
Synonyms	POPG Sodium Salt; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; (Rac)-1-Palmitoyl-2-oleoylphosphatidylglycerol sodium salt; POPG-Na; PG(16:0/18:1) Sodium Salt; 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt; Phosphatidylglycerol (16:0/18:1) Sodium Salt
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Oleyl-Sn-Glycero-3-Phospho-Rac-(1-Glycerol) Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, and TLC for lipid profile analysis, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (Total Phospholipid Content)
Purity (HPLC, Single Component)	≥ 95.0%
Solubility	Soluble in chloroform, methanol; forms dispersions in water
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	< 2.0 %
Peroxide Value	< 3.0 meq/kg
Bacterial Endotoxins	< 1.0 EU/mg (for injectable grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.