Description

2-Deoxy-2,3-Didehydro-n-Glycoloylneuraminic Acid is a chemically modified derivative of sialic acid, a critical carbohydrate found in glycoproteins and glycolipids. This compound serves as a valuable intermediate and research tool in the study of sialidase enzymes and carbohydrate-based biological processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing enzyme inhibitors, glycan analysis, and investigating cell surface interactions.

Application

• Sialidase (Neuraminidase) Inhibition Studies: Used as a substrate analog to investigate enzyme kinetics and develop potential inhibitors for viral and bacterial neuraminidases.
• Glycobiology Research: A key intermediate for synthesizing complex oligosaccharides and studying sialic acid metabolism and signaling pathways.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of novel antiviral and antibacterial agents targeting sialic acid-dependent mechanisms.
• Diagnostic Reagent Development: Employed in the formulation of assays and kits for detecting sialidase activity or specific carbohydrate-protein interactions.
• Bioconjugation and Probe Synthesis: Used to create labeled probes for fluorescence imaging or other detection methods to study glycan localization on cell surfaces.

Basic Information

Product Name	2-Deoxy-2,3-Didehydro-n-Glycoloylneuraminic Acid
CAS No.	39937-91-2
Molecular Formula	C11H15NO9
Molecular Weight	305.24 g/mol
Synonyms	DANA Glycoloyl Derivative; 2-Deoxy-2,3-didehydro-N-glycoloylneuraminic Acid; 5-Acetamido-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic Acid (Glycoloyl); N-Glycoloyl-2,3-didehydro-2-deoxyneuraminic Acid; 2,3-Didehydro-2-deoxy-N-glycoloylneuraminic Acid; Neu5Gc2en; Anti-influenza Agent Intermediate
EINECS	Contact for details

Quality Control

Our 2-Deoxy-2,3-Didehydro-n-Glycoloylneuraminic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.