Description

Chloramphenicol Glucuronide is a crucial metabolite and analytical reference standard derived from the antibiotic chloramphenicol. This compound is essential for researchers and quality control laboratories requiring precise analytical benchmarks. It is primarily used in pharmaceutical research, clinical diagnostics, and regulatory testing to study drug metabolism, ensure product safety, and monitor residues.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the quantification and identification of chloramphenicol and its metabolites in drug substance and product analysis.
• Clinical & Diagnostic Research: Used in developing and validating bioanalytical methods (e.g., LC-MS/MS, HPLC) for studying chloramphenicol pharmacokinetics and metabolism in biological fluids.
• Veterinary Drug Residue Testing: A critical standard in food safety laboratories for monitoring and confirming chloramphenicol glucuronide residues in animal-derived products (meat, milk, honey) to ensure compliance with MRLs (Maximum Residue Limits).
• Metabolite Profiling: Employed in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to understand the metabolic pathways and clearance mechanisms of chloramphenicol.
• Quality Control & Method Development: Essential for calibrating equipment and validating analytical procedures in GMP/GLP environments for accurate and reproducible results.

Basic Information

Product Name	Chloramphenicol Glucuronide
CAS No.	39751-33-2
Molecular Formula	C21H23Cl2N2O11
Molecular Weight	550.32 g/mol
Synonyms	Chloramphenicol β-D-Glucuronide; Chloramphenicol Glucuronide Sodium Salt; D-threo-Chloramphenicol Glucuronide; 2-[(2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamido)methyl]-6-(1,2,3,4,5-pentahydroxypentyl)oxane-3,4,5-triol; CAP Glucuronide; Chloramphenicol 3-O-β-D-Glucuronide
EINECS	Contact for details

Quality Control

Our Chloramphenicol Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for use as a reference material. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.