Description

Amino-Peg6-Alcohol is a heterobifunctional polyethylene glycol (PEG) derivative featuring a primary amine and a terminal hydroxyl group, connected by a hexaethylene glycol spacer. This bifunctionality is critical for creating hydrophilic, biocompatible linkers in bioconjugation and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostics sectors for modifying peptides, proteins, and surfaces to enhance solubility and reduce immunogenicity.

Application

• Bioconjugation Linker: Used to conjugate drugs, dyes, or other functional molecules to antibodies, proteins, or peptides, improving pharmacokinetics.
• PEGylation Reagent: Serves as a building block for creating custom PEGylated therapeutics to enhance stability and circulation time.
• Surface Modification: Functionalizes nanoparticles, biosensors, and medical devices to create non-fouling, hydrophilic surfaces.
• Crosslinking Agent: Acts as a spacer in the synthesis of hydrogels and polymer networks for controlled drug delivery systems.
• Intermediate for ADC Development: A key reagent in the synthesis of antibody-drug conjugates (ADCs), providing a cleavable or non-cleavable linker.
• Diagnostic Probe Synthesis: Facilitates the attachment of targeting ligands to imaging agents for in vitro and in vivo diagnostics.

Basic Information

Product Name	Amino-Peg6-Alcohol
CAS No.	39160-70-8
Molecular Formula	C14H31NO7
Molecular Weight	325.40 g/mol
Synonyms	2,5,8,11,14,17-Hexaoxanonadecan-19-amine; 19-Amino-3,6,9,12,15-pentaoxaheptadecan-1-ol; 1-Amino-3,6,9,12,15-pentaoxaheptadecan-17-ol; NH2-PEG6-OH; Amine-PEG6-alcohol; 17-Amino-3,6,9,12,15-pentaoxaheptadecan-1-ol; Heterobifunctional PEG6; Amino-PEG6-OH
EINECS	Contact for details

Quality Control

Our Amino-Peg6-Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for sensitive bioconjugation applications. Certificates of Analysis (COA) with detailed specifications are provided to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Amine Value (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.