Description

(-)-Porantheridine CAS NO 39027-77-5 is a specific enantiomer of the porantheridine alkaloid, a compound of significant interest in advanced organic synthesis and pharmaceutical research. Its defined stereochemistry makes it a valuable chiral building block and a reference standard for the study of related natural products. This high-purity compound is essential for researchers and developers in the pharmaceutical, agrochemical, and fine chemical sectors who require precise molecular tools for drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate biological pathways and receptor interactions.
• Asymmetric Synthesis: Employed as a sophisticated chiral building block or catalyst ligand in stereoselective chemical transformations.
• Natural Product Synthesis: Acts as a critical intermediate in the total synthesis of complex alkaloids and other natural products for structure-activity relationship (SAR) studies.
• Analytical Standard: Provides a high-purity benchmark for quality control, method development, and impurity profiling in analytical laboratories (HPLC, GC, LC-MS).
• Agrochemical Development: Investigated as a potential intermediate for creating novel, enantiomerically pure crop protection agents.

Basic Information

Product Name	(-)-Porantheridine
CAS No.	39027-77-5
Molecular Formula	C14H21NO2
Molecular Weight	235.33 g/mol
Synonyms	(3R,5S,7aR)-5-Ethyl-3-methyloctahydro-1H-indol-7a-ol; Porantheridine, (-)-; (-)-Porantheridine; L-Porantheridine; Porantheridine [(-)-form]; (3R,5S,7aR)-5-Ethyl-3-methyloctahydroindol-7a-ol; 1H-Indol-7a-ol, octahydro-5-ethyl-3-methyl-, (3R,5S,7aR)-
EINECS	Contact for details

Quality Control

Our (-)-Porantheridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage, consider keeping the product under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.