Description

n-Acetyl-n-Demethylloline is a specialized alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial high-purity building block and reference standard for developing novel active pharmaceutical ingredients (APIs) and studying complex biochemical pathways. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in cutting-edge medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new therapeutic agents.
• Biochemical Research: Used as a reference standard and probe in pharmacological and metabolic pathway studies.
• Organic Synthesis: Acts as a versatile building block for constructing complex alkaloid-based molecular architectures.
• Analytical Standard: Employed for method development, calibration, and quality control in analytical laboratories (HPLC, LC-MS).
• Academic Research: Utilized in university and institutional labs for studies in natural product chemistry and synthetic methodology.
• Process Chemistry: Investigated for scale-up and optimization in the production of fine chemicals and advanced intermediates.

Basic Information

Product Name	n-Acetyl-n-Demethylloline
CAS No.	38964-35-1
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	N-Acetylnordemethylloline; N-Acetyl-N-demethylloline; Loline alkaloid derivative; 1-Acetyl-1,2-dehydro-8-demethylloline; 2,3,5,6,7,8-Hexahydro-1H-pyrrolizin-1-one, 2-acetyl-2,3,3a,4,5,7a-hexahydro-; (3aR,7aR)-2-Acetyl-2,3,3a,4,5,7a-hexahydro-1H-pyrrolizin-1-one
EINECS	Contact for details

Quality Control

Our n-Acetyl-n-Demethylloline is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.