Description

7,8-Dihydrobatrachotoxin A is a potent steroidal alkaloid derivative, a key intermediate in the study of neurotoxic compounds. Its primary value lies in advanced biochemical and pharmacological research, particularly for investigating sodium channel function and modulation. This high-purity compound is essential for specialized laboratories in the pharmaceutical, toxicology, and neuroscience sectors requiring precise tools for receptor binding studies and toxin mechanism analysis.

Application

• Neuroscience Research: Critical tool for studying voltage-gated sodium channels (Nav channels) and their role in neuronal signaling.
• Pharmacological Studies: Used as a reference standard and active agent in research focused on neurotoxins and their mechanisms of action.
• Toxicology & Safety Science: Employed in the development of detection methods and antidote research for batrachotoxin-related compounds.
• Biochemical Assay Development: Serves as a high-potency ligand in receptor binding assays and other in vitro test systems.
• Academic & Institutional Research: Used by universities and government research institutes for fundamental studies in neurobiology and chemical ecology.
• Pharmaceutical R&D: Valuable intermediate for exploring novel therapeutic targets related to pain, cardiac function, and neurological disorders.

Basic Information

Product Name	7,8-Dihydrobatrachotoxin A
CAS No.	38930-41-5
Molecular Formula	C31H42N2O6
Molecular Weight	538.68 g/mol
Synonyms	7,8-Dihydrobatrachotoxin; Dihydrobatrachotoxin A; Batrachotoxin Derivative; 20α-7,8-Dihydrobatrachotoxinin A 3α,9α-epoxy-14β,18β-(2-methyl-1H-pyrrole-3,4-diyl)diacetate; (3α,9α,14β,18β)-3,9-Epoxy-14,18-[(2-methyl-1H-pyrrole-3,4-diyl)bis(oxy)]batrachotoxanin 20-ol
EINECS	Contact for details

Quality Control

Our 7,8-Dihydrobatrachotoxin A is produced under stringent conditions to ensure the highest standards of purity and identity required for sensitive research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.