Description

Ndsb-211 is a specialized chemical compound, identified by CAS NO 38880-58-9, valued for its unique properties as a non-detergent sulfobetaine. This compound is essential for biochemical and biotechnological research, where it is used to stabilize proteins and enzymes without denaturing them. It is a critical reagent for laboratories and industries focused on protein purification, electrophoresis, and molecular biology applications.

Application

• Protein Solubilization and Stabilization: Used as a zwitterionic detergent alternative to solubilize membrane proteins while maintaining their native structure and function.
• Electrophoresis: Employed in two-dimensional gel electrophoresis (2D-PAGE) as a chaotrope and surfactant in sample preparation buffers to improve protein separation and resolution.
• Chromatography: Serves as an additive in liquid chromatography to enhance the recovery and purification of sensitive biomolecules.
• Cell Lysis: An effective component in lysis buffers for gentle disruption of cells and organelles to extract intact proteins and nucleic acids.
• Diagnostic Reagent Formulation: Used in the formulation of buffers and reagents for in-vitro diagnostic kits and assays.
• Pharmaceutical Research: Applied in biopharmaceutical development for studying protein-protein interactions and formulation stability.

Basic Information

Product Name	Ndsb-211
CAS No.	38880-58-9
Molecular Formula	C7H17NO3S
Molecular Weight	195.28 g/mol
Synonyms	3-(1-Pyridinio)-1-propanesulfonate; NDSB-211; Non-detergent sulfobetaine 211; 1-(3-Sulfopropyl)pyridinium hydroxide, inner salt; 3-(N-Pyridinio)propanesulfonate; Zwittergent 3-10; SPY; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Ndsb-211 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) to ensure the material meets the high standards required for research and industrial applications. Specifications are aligned with common biochemical reagent grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
pH (10% solution)	6.0 - 8.0
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.