Description

Tetrahydroepiberberine, Sinactine CAS NO 38853-67-7 is a high-purity, naturally-derived isoquinoline alkaloid known for its significant biological activity. This compound is of critical importance for research and development in the pharmaceutical and nutraceutical sectors, serving as a key intermediate or reference standard. It is primarily sought by manufacturers and research institutions focused on developing therapeutic agents, particularly for metabolic and neurological applications. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency and reliability for demanding industrial and research use.

Application

• Pharmaceutical intermediate for the synthesis of novel therapeutic agents.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Key starting material in research for metabolic disorder treatments.
• Active ingredient in advanced nutraceutical and dietary supplement formulations.
• Biochemical research tool for studying enzyme inhibition and receptor interactions.
• Precursor for the development of high-value specialty fine chemicals.

Basic Information

Product Name	Tetrahydroepiberberine, Sinactine
CAS No.	38853-67-7
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	Sinactine; Tetrahydroepiberberine; 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine; (-)-Sinactine; (13aS)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine; NSC 34156; Epiberberine tetrahydro derivative
EINECS	Contact for details

Quality Control

Our Tetrahydroepiberberine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.