Description

3-[[(Nonyloxy)Imino]Methyl]Rifamycin is a chemically modified derivative of the potent ansamycin antibiotic rifamycin. This semi-synthetic compound is engineered to enhance stability and bioavailability for advanced pharmaceutical research and development. It serves as a critical intermediate and active pharmaceutical ingredient (API) for researchers and manufacturers in the antimicrobial and anti-infective sectors, targeting drug-resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of next-generation rifamycin-class antibiotics.
• Antimicrobial Research: Used in R&D for studying structure-activity relationships against Mycobacterium tuberculosis and other Gram-positive bacteria.
• API Manufacturing: Serves as an active pharmaceutical ingredient in the production of specialized anti-tuberculosis and anti-staphylococcal medications.
• Veterinary Medicine: Potential application in developing treatments for bacterial infections in animals.
• Biochemical Tool: Utilized in laboratory studies to investigate bacterial RNA polymerase inhibition mechanisms.

Basic Information

Product Name	3-[[(Nonyloxy)Imino]Methyl]Rifamycin
CAS No.	38850-20-3
Molecular Formula	C43H58N2O12
Molecular Weight	794.93 g/mol
Synonyms	3-[(Nonyloxyimino)methyl]rifamycin; Rifamycin, 3-[[(nonyloxy)imino]methyl]-; 3-Formylrifamycin SV O-(nonyloxime); Rifamycin O-nonyloxime; Rifamycin derivative 38850-20-3; (E)-3-((Nonyloxyimino)methyl)rifamycin; Rifampicin analog; Antibiotic XZ-450
EINECS	Contact for details

Quality Control

Our 3-[[(Nonyloxy)Imino]Methyl]Rifamycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with relevant pharmaceutical intermediate standards. Specifications can be aligned with client-specific pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	Orange-red to brownish-red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.