Description

5'-Deoxy-5-Fluorouridine is a fluorinated pyrimidine nucleoside analog, a key intermediate in the synthesis of advanced pharmaceutical compounds. This compound matters for its role as a crucial building block in the development of novel antiviral and anticancer agents, enabling targeted therapeutic research. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in nucleoside chemistry and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced antiviral and anticancer nucleoside analogs.
• Oncology Research: Used in biochemical research to study cell proliferation mechanisms and develop targeted cancer therapies.
• Antiviral Drug Development: Serves as a building block for creating novel antiviral medications.
• Biochemical Studies: Employed as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism.
• Fine Chemical Synthesis: Utilized in custom synthesis and process development for high-value specialty chemicals.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical manufacturing.

Basic Information

Product Name	5'-Deoxy-5-Fluorouridine
CAS No.	38817-29-7
Molecular Formula	C9H11FN2O5
Molecular Weight	246.19 g/mol
Synonyms	5'-Deoxy-5-fluorouridine; 5-Fluoro-5'-deoxyuridine; 5-Fluoro-2'-deoxyuridine 5'-deoxy; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-1-(5-deoxy-β-D-ribofuranosyl)uracil; 5-FdUrd; 5'-dFUrd; DFUR (Note: Often confused with Doxifluridine, which is its prodrug).
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5-Fluorouridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.