Description

(2α,5α,16S)-2,5-Epoxy-1,2-Dihydroakuammilan-17-Oic Acid Methyl Ester CAS NO 38801-86-4 is a high-purity, complex indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and study of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly in the exploration of neurological and pharmacological agents.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method development in drug manufacturing.
• Drug Discovery Intermediate: Serves as a key synthetic building block for the creation of new alkaloid-based therapeutic candidates.
• Biochemical Research: Employed in academic and industrial laboratories to study structure-activity relationships (SAR) and biological pathways.
• Analytical Chemistry: Utilized as an internal standard or marker in chromatographic analyses (HPLC, LC-MS) for natural product quantification.
• Natural Product Synthesis: A pivotal compound in the semi-synthesis of complex indole alkaloids for medicinal chemistry programs.

Basic Information

Product Name	(2α,5α,16S)-2,5-Epoxy-1,2-Dihydroakuammilan-17-Oic Acid Methyl Ester
CAS No.	38801-86-4
Molecular Formula	C21H24N2O4
Molecular Weight	368.43 g/mol
Synonyms	Methyl (2α,5α,16S)-2,5-epoxy-1,2-dihydroakuammilan-17-oate; 2,5-Epoxy-1,2-dihydroakuammilan-17-oic acid methyl ester; Akuammilan-17-oic acid, 2,5-epoxy-1,2-dihydro-, methyl ester, (2α,5α,16S)-; Strictosidine lactam derivative
EINECS	Contact for details

Quality Control

Our (2α,5α,16S)-2,5-Epoxy-1,2-Dihydroakuammilan-17-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.