Description

Mannopentaose-Di(n-Acetyl-D-Glucosamine)-Asparagine is a defined, high-purity oligosaccharide-asparagine conjugate, a key structural motif in glycobiology research. This compound matters as a critical reference standard and building block for studying N-linked glycosylation pathways and glycan-protein interactions. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise tools for glycoprotein analysis, vaccine development, and the synthesis of complex glycoconjugates.

Application

• Glycobiology Research: Used as a reference standard and substrate for studying enzyme kinetics of glycosyltransferases and glycosidases.
• Pharmaceutical Development: Serves as a key intermediate and analytical standard in the development of glycoprotein-based therapeutics, including monoclonal antibodies and vaccines.
• Diagnostic Reagent Synthesis: Employed in the production of high-specificity reagents for detecting and quantifying specific glycan structures in clinical samples.
• Biochemical Tool: Acts as a well-defined acceptor molecule for enzymatic or chemical synthesis of more complex N-glycan structures.
• Quality Control: Utilized as a calibration standard in analytical methods (HPLC, MS) to ensure the consistency and purity of glycoprotein products.
• Academic Research: Fundamental tool for investigating the role of specific N-glycan structures in cell signaling, immune response, and disease mechanisms.

Basic Information

Product Name	Mannopentaose-Di(n-Acetyl-D-Glucosamine)-Asparagine
CAS No.	38784-68-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Man5GlcNAc2-Asn; (Man)5(GlcNAc)2-Asn; N-Glycan core pentamannosyl structure linked to asparagine; Asparagine-linked pentamannose chitobiose; Oligomannose-type N-glycan-Asn conjugate; High-mannose N-glycan core structure
EINECS	Contact for details

Quality Control

Every batch of Mannopentaose-Di(n-Acetyl-D-Glucosamine)-Asparagine is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, mass spectrometry, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to prevent condensation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay	≥ 98% (on dried basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.