Description

Leucyl-Phenylalanine Amide CAS NO 38678-60-3 is a high-purity dipeptide derivative, specifically the amide of the Leu-Phe dipeptide. This compound serves as a critical building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by pharmaceutical R&D teams, peptide synthesis specialists, and biochemical research laboratories for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate peptide metabolism.
• Peptide Library Synthesis: An essential component for constructing diverse peptide libraries in drug discovery and high-throughput screening.
• Protease/Enzyme Studies: Serves as a model compound to study the specificity and kinetics of proteolytic enzymes like chymotrypsin or leucine aminopeptidases.
• Cosmetic Peptide Synthesis: Potential intermediate for synthesizing bioactive peptides used in advanced skincare and cosmetic formulations.
• Academic & Institutional Research: A valuable reagent for universities and research institutes studying peptide chemistry, medicinal chemistry, and structural biology.

Basic Information

Item	Detail
Product Name	Leucyl-Phenylalanine Amide
CAS No.	38678-60-3
Molecular Formula	C15H23N3O2
Molecular Weight	277.36 g/mol
Synonyms	L-Leucyl-L-phenylalaninamide; H-Leu-Phe-NH2; Leu-Phe amide; N-(1-Oxo-1-(((1-oxo-3-phenyl-2-(phenylmethyl)propyl)amino)pentyl)-L-phenylalanine amide; L-Phenylalanine, L-leucyl-, amide; (S)-2-((S)-2-Amino-4-methylpentanamido)-3-phenylpropanamide; Peptide building block Leu-Phe-NH2
EINECS	Contact for details

Quality Control

Our Leucyl-Phenylalanine Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity analysis, and identity confirmation by spectroscopic methods. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results against our stringent in-house specifications to ensure batch-to-batch consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L, L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.