Description

(2S,5R)-2,5-Hexanediol CAS NO 38484-55-8 is a high-purity, stereochemically defined diol compound, serving as a critical chiral building block in advanced organic synthesis. Its defined stereochemistry is essential for producing enantiomerically pure intermediates, which are vital for ensuring the efficacy and safety of final products. This material is primarily needed by the pharmaceutical, agrochemical, and specialty polymer industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drug development.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance activity and reduce environmental impact.
• Liquid Crystal Monomer: Acts as a chiral spacer or terminal group in the synthesis of liquid crystal materials for advanced display technologies.
• Polymer Modifier: Incorporated into specialty polyesters and polyurethanes to impart specific physical properties or biodegradability.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands used in metal-catalyzed asymmetric reactions.
• Flavor and Fragrance Ingredient: Used in the synthesis of specific chiral aroma chemicals.

Basic Information

Product Name	(2S,5R)-2,5-Hexanediol
CAS No.	38484-55-8
Molecular Formula	C6H14O2
Molecular Weight	118.17 g/mol
Synonyms	(2S,5R)-(-)-2,5-Hexanediol; (2S,5R)-Hexane-2,5-diol; (-)-2,5-Hexanediol; (S,R)-2,5-Hexanediol; 2,5-Dihydroxyhexane (stereospecific); L(-)-2,5-Hexanediol; (2S,5R)-1,2,5,6-Hexanetetrol (misnomer, but sometimes used); meso-2,5-Hexanediol (Note: This is a different stereoisomer)
EINECS	Contact for details

Quality Control

Our (2S,5R)-2,5-Hexanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect quality.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	60 - 64 °C
Specific Rotation [α]	-15.0° to -18.0° (c=1 in H2O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.