Description

(5α,12β,19α,20S)-2,3-Didehydro-20-Hydroxy-7-Oxoaspidospermidine-3-Carboxylic Acid Methyl Ester is a high-purity, structurally complex indole alkaloid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a sophisticated molecular scaffold for the research and development of novel pharmaceutical agents, particularly in oncology and neurological studies. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable access to high-quality building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, especially those targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of novel bioactive molecules with potential therapeutic applications.
• Alkaloid Chemistry Studies: Employed in academic and industrial research focused on the synthesis, modification, and biological evaluation of aspidosperma-type indole alkaloids.
• Process Chemistry Development: Acts as a model compound for developing and optimizing scalable synthetic routes for complex natural product derivatives.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in chromatographic analysis (HPLC, LC-MS).
• Biochemical Probe Development: Provides a specialized chemical structure for creating probes to study enzyme interactions or cellular mechanisms.

Basic Information

Product Name	(5α,12β,19α,20S)-2,3-Didehydro-20-Hydroxy-7-Oxoaspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	38225-09-1
Molecular Formula	C21H24N2O4
Molecular Weight	368.43 g/mol
Synonyms	20-Hydroxy-7-oxoaspidospermidine-3-carboxylic acid methyl ester; Methyl (5α,12β,19α,20S)-2,3-didehydro-20-hydroxy-7-oxoaspidospermidine-3-carboxylate; 7-Oxoaspidospermidine derivative; Aspidosperma alkaloid intermediate; 38225-09-1; UNII-7Q5F5P4T3R
EINECS	Contact for details

Quality Control

Our (5α,12β,19α,20S)-2,3-Didehydro-20-Hydroxy-7-Oxoaspidospermidine-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.