Description

Ganglioside Gm1, Ammonium Salt, Bovine is a high-purity, naturally sourced glycosphingolipid, specifically the ammonium salt form of the monosialotetrahexosylganglioside GM1 isolated from bovine brain. This compound is a critical biochemical reagent valued for its role in modulating cellular signaling, neuronal function, and membrane dynamics. It is essential for researchers and manufacturers in the fields of neuroscience, biochemistry, and pharmaceutical development, particularly for studying neurodegenerative diseases, receptor interactions, and as a potential component in advanced therapeutic formulations.

Application

• Neuroscience Research: Used as a standard and reagent in studies of neuronal growth, differentiation, and the pathogenesis of disorders like Alzheimer's and Parkinson's disease.
• Cell Biology & Signal Transduction: Employed to investigate the role of gangliosides in cell membrane structure, lipid raft formation, and intracellular signaling pathways.
• Biochemical Standard: Serves as a high-purity reference standard for analytical methods such as HPLC, TLC, and mass spectrometry in quality control and research laboratories.
• Pharmaceutical R&D: Explored as a potential active pharmaceutical ingredient (API) or excipient in novel drug delivery systems and neuroprotective therapies.
• Diagnostic Development: Utilized in the development of immunoassays and diagnostic kits targeting ganglioside-related biomarkers.

Basic Information

Product Name	Ganglioside Gm1, Ammonium Salt, Bovine
CAS No.	37758-47-7
Molecular Formula	C~73~H~134~N~2~O~31~ • xNH~3~
Molecular Weight	Approx. 1566.8 (for free acid, excluding NH~3~)
Synonyms	GM1 Ganglioside, Ammonium Salt; Monosialotetrahexosylganglioside GM1; II3Neu5Ac-Gg4Cer; Ganglioside GM1 (Bovine); Tay-Sachs ganglioside GM1; Ammonium GM1; AS-1; GMR-6; GgOse4Cer-NeuAc
EINECS	Contact for details

Quality Control

Our Ganglioside Gm1, Ammonium Salt, Bovine is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), identity (by TLC and MS), and residual solvents are provided to guarantee traceability and compliance with your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (TLC)	Conforms to standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform/methanol mixtures, DMSO
Loss on Drying	≤ 5.0 %
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.