Description

Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11-Hydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Alpha)- is a high-purity, water-soluble corticosteroid derivative, specifically a monosodium salt form designed for enhanced formulation stability and bioavailability. This compound is critical for pharmaceutical research and development, offering a key intermediate or active ingredient for advanced therapeutic applications. It is primarily sought by manufacturers and R&D laboratories in the pharmaceutical and biotechnology sectors for the development of potent anti-inflammatory and immunosuppressive medications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced corticosteroid-based active pharmaceutical ingredients (APIs).
• Anti-inflammatory Drug Development: Used in R&D for formulating topical, injectable, or oral medications targeting severe inflammation and autoimmune disorders.
• Immunosuppressive Therapy Research: A critical component in the study and development of drugs for organ transplantation and immune-mediated diseases.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Veterinary Pharmaceutical Formulations: Used in developing anti-inflammatory treatments for companion and livestock animals.
• Biochemical Research: Utilized in academic and industrial research to study glucocorticoid receptor interactions and signaling pathways.

Basic Information

Product Name	Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11-Hydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Alpha)-
CAS No.	37413-97-1
Molecular Formula	C29H32FO8S•Na
Molecular Weight	582.62 g/mol
Synonyms	9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-(3-sulfobenzoate) monosodium salt; 21-(3-Carboxy-1-oxopropoxy)-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione monosodium salt; Betamethasone 21-(3-sulfobenzoate) sodium salt; Sodium betamethasone sulfobenzoate; Betamethasone sodium sulfobenzoate; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-(3-sulfobenzoate) monosodium salt
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione, 9-Fluoro-11-Hydroxy-16-Methyl-21-[(3-Sulfobenzoyl)Oxy]-, Monosodium Salt, (11Beta,16Alpha)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications suitable for pharmaceutical R&D. Certificates of Analysis (COA) detailing all test results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.