Description

Dextran Dialdehyde CAS NO 37317-99-0 is a chemically modified polysaccharide derivative, created by the controlled periodate oxidation of dextran, which introduces reactive aldehyde groups along the polymer backbone. This functionalization is critical, as it enables the compound to act as a versatile cross-linking and immobilization agent for biomolecules. It is an essential material for researchers and manufacturers in the life sciences and biomedical engineering sectors who require reliable, high-purity reagents for advanced applications.

Application

• Bioconjugation and Protein Immobilization: Used to covalently bind proteins, enzymes, and antibodies to solid supports or other polymers for diagnostic assays, biosensors, and affinity chromatography.
• Hydrogel Formation for Tissue Engineering: Serves as a key cross-linker for creating biocompatible and biodegradable hydrogels used in wound dressings, drug delivery systems, and 3D cell culture scaffolds.
• Cell Encapsulation and Microcarriers: Employed to encapsulate living cells or create functionalized microcarriers for cell therapy and bioreactor applications.
• Hemostatic Agents and Surgical Adhesives: Utilized in the formulation of advanced hemostats and tissue adhesives that promote rapid clotting and wound closure.
• Chromatography Media Modification: Functionalizes agarose or other chromatography beads to create aldehyde-activated resins for the purification of biomolecules.
• Vaccine Adjuvant Development: Investigated as a component in novel vaccine delivery systems to enhance immune response through antigen presentation.

Basic Information

Product Name	Dextran Dialdehyde
CAS No.	37317-99-0
Molecular Formula	(C6H10O5)n·(C6H8O5)m
Molecular Weight	Variable (based on dextran starting material and degree of oxidation)
Synonyms	Oxidized Dextran; Dialdehyde Dextran; Dextran, oxidized; Poly(aldehyde dextran); Dextran dialdehyde polymer; Periodate-oxidized dextran; Aldehyde-functionalized dextran; DexOx; DAD
EINECS	Contact for details

Quality Control

Our Dextran Dialdehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure consistent performance, including determination of the degree of aldehyde substitution, molecular weight distribution, and purity. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (IR)	Conforms to structure
Assay (Aldehyde Content)	Typically 10-50% oxidation (customizable)
Molecular Weight (Mw)	Customized (e.g., 10kDa, 40kDa, 70kDa, 500kDa)
Solubility	Soluble in water, aqueous buffers
pH (1% solution)	4.0 - 7.0
Residual Periodate	< 0.1%
Endotoxin Level	< 1.0 EU/mg (for specific grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.