Description

D-Transaminase, Broad-Range is a highly versatile biocatalyst enzyme belonging to the class of transaminases (aminotransferases). This enzyme is critical for the stereoselective synthesis of chiral amines and amino acids, which are key building blocks in pharmaceutical and fine chemical manufacturing. It is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and biotechnology industries seeking efficient, green chemistry routes for asymmetric synthesis.

Application

• Pharmaceutical Intermediate Synthesis: Key for the production of chiral amine APIs (Active Pharmaceutical Ingredients) and unnatural amino acids.
• Asymmetric Catalysis: Enables green, enzymatic routes for the synthesis of enantiomerically pure compounds, replacing traditional metal-catalyzed methods.
• Biocatalysis Process Development: Used in R&D for developing scalable, sustainable manufacturing processes for fine chemicals.
• Agrochemical Manufacturing: Applied in the synthesis of chiral intermediates for herbicides, fungicides, and insecticides.
• Diagnostic Reagent Formulation: Serves as a component in enzymatic assay kits for clinical and research diagnostics.
• Food & Flavor Ingredient Production: Used in the biocatalytic synthesis of certain flavor compounds and nutritional supplements.

Basic Information

Product Name	D-Transaminase, Broad-Range
CAS No.	37277-85-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	D-Aminotransferase; D-Transaminase; D-TA; (R)-Selective Transaminase; ω-Transaminase; Broad-Substrate-Specificity Transaminase; D-ATA; PLP-Dependent D-Aminotransferase; EC 2.6.1.-
EINECS	Contact for details

Quality Control

Our D-Transaminase, Broad-Range is produced and tested under strict quality management systems. Each batch is characterized for specific activity, purity, and stability to ensure consistent performance in biocatalytic applications. A comprehensive Certificate of Analysis (COA) detailing enzyme activity (U/mg), protein content, and purity is provided with every shipment. We support compliance with cGMP and ISO 9001 standards for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term stability, consider storage at -20°C under desiccant. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Specific Activity	≥ 5 U/mg protein
Protein Content (Biuret)	≥ 90%
Purity (SDS-PAGE)	Single major band
pH Stability	7.0 - 9.0
Temperature Optimum	30 - 50°C
Solubility	Soluble in buffer (e.g., phosphate, Tris-HCl)
Identification (IR / Enzyme Assay)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.