Description

α-1 3-Fucosyl Transferase Vi Recombi is a highly specific recombinant enzyme that catalyzes the transfer of fucose from GDP-fucose to acceptor substrates with terminal N-acetyllactosamine structures. This precision is critical for the synthesis of complex carbohydrates and glycoconjugates, particularly those containing the sialyl Lewis X (sLex) epitope. It is an essential tool for researchers and manufacturers in the biotechnology and pharmaceutical industries, enabling advanced studies in glycobiology and the development of novel therapeutics and diagnostic reagents.

Application

• Glycoconjugate Synthesis: Enzymatic synthesis of sialyl Lewis X (sLex) and related carbohydrate structures for research and diagnostic applications.
• Biopharmaceutical Development: Used in the production and quality control of therapeutic proteins, monoclonal antibodies, and vaccines where specific glycosylation patterns are critical for efficacy and safety.
• Glycoengineering: A key reagent for modifying the glycosylation profiles of proteins and cell surfaces to study function or improve therapeutic properties.
• Diagnostic Reagent Production: Manufacture of enzyme-linked assays and other diagnostic tools that detect specific carbohydrate antigens.
• Biochemical Research: Fundamental research into fucosylation pathways, cell-cell recognition, inflammation, and cancer metastasis.
• Enzyme Characterization Studies: Serves as a standard or reference material for studying enzyme kinetics, specificity, and inhibition.

Basic Information

Product Name	α-1 3-Fucosyl Transferase Vi Recombi
CAS No.	37277-69-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fucosyltransferase 6 (FUT6); Alpha(1,3)Fucosyltransferase; GDP-L-Fucose:β-D-Galactoside 3-α-L-Fucosyltransferase; Fuc-TVI; Recombinant Fucosyltransferase VI; EC 2.4.1.65; α-1,3-Fucosyltransferase Recombinant
EINECS	Contact for details

Quality Control

Our recombinant α-1 3-Fucosyl Transferase is produced under stringent conditions to ensure high purity, specific activity, and batch-to-batch consistency. Each lot is subjected to a comprehensive suite of analytical tests, including activity assays, purity assessment by SDS-PAGE and HPLC, and tests for endotoxin and bioburden. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance in research and cGMP-guided applications where required.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. Aliquot the product upon receipt for single-use applications to maintain optimal enzymatic activity.

Specification

Item	Specification
Appearance	Clear to slightly opalescent solution
Identification (Activity)	Conforms
Protein Concentration	≥ 0.5 mg/mL
Specific Activity	≥ 50 mU/mg
Purity (SDS-PAGE)	≥ 90%
Endotoxin	< 1.0 EU/μg
Buffer	Tris-HCl, Glycerol, pH ~7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.