Description

Wilfordine is a naturally occurring sesquiterpene alkaloid isolated from plants of the *Tripterygium* genus, such as *Tripterygium wilfordii* (Thunder God Vine). This compound is of significant interest in pharmaceutical research and development due to its potent biological activities. It serves as a critical reference standard and active pharmaceutical ingredient (API) for researchers and manufacturers in the life sciences sector. Key target industries include pharmaceutical R&D, biotechnology, and academic institutions focused on immunology and oncology.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and finished pharmaceutical products in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key starting material or intermediate in the synthesis of novel therapeutic agents.
• Biomedical Research: Employed in in vitro and in vivo studies to investigate its immunomodulatory, anti-inflammatory, and potential anti-cancer properties.
• Natural Product Isolation & Standardization: Essential for standardizing extracts of *Tripterygium wilfordii*, ensuring batch-to-batch consistency and efficacy.
• Analytical Method Development: Used as a high-purity calibrant in developing and validating HPLC, LC-MS, and other chromatographic methods.

Basic Information

Product Name	Wilfordine
CAS No.	37239-51-3
Molecular Formula	C43H49NO19
Molecular Weight	883.85 g/mol
Synonyms	Wilfordine; NSC 329962; (1S,2S,5S,7S,10R,11S,14S,15R,16S,18S,20S,21R,24S,25R,28S,29R,30S,32S,34S,35R,38S,39R,40S,42S,44S,45R,48S,49R,50S,52S,54S,55R,58S,59R,60S,62S,64S,65R,68S,69R,70S,72S,74S,75R)-2,7,11,15,18,21,25,29,32,35,39,42,45,49,52,55,59,62,65,69,72,75-Tetratriacontahydroxy-16,20,24,28,30,34,38,40,44,48,50,54,58,60,64,68,70,74-octadecaoxa-5-azanonacyclo[27.25.0.01,5.01,30.02,7.010,15.011,16.014,20.021,25.024,29.032,35.034,39.038,44.040,45.042,48.049,54.050,55.052,59.058,64.060,65.062,69.068,74]heptatriacontan-70-one (IUPAC); Tripterygium wilfordii alkaloid.
EINECS	Contact for details

Quality Control

Our Wilfordine is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.