Description

Dansyl Phosphatidylethanolamine is a fluorescently labeled phospholipid derivative, where the dansyl fluorophore is covalently attached to the headgroup of phosphatidylethanolamine. This compound is a critical tool in biophysical and biochemical research for studying membrane dynamics, lipid-protein interactions, and vesicle trafficking due to its strong fluorescence and environmental sensitivity. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical R&D, and diagnostic reagent manufacturing sectors.

Application

• Membrane Biophysics Research: As a fluorescent probe for investigating lipid bilayer properties, phase transitions, and membrane fluidity.
• Lipid-Protein Interaction Studies: To label membranes for Förster Resonance Energy Transfer (FRET) assays or fluorescence quenching experiments with membrane-associated proteins.
• Liposome & Vesicle Tracking: Used to fluorescently tag liposomes for tracking cellular uptake, intracellular trafficking, and biodistribution studies in drug delivery research.
• Cell Biology Assays: Employed in fluorescence microscopy and flow cytometry to visualize and quantify membrane fusion, endocytosis, and exocytosis events.
• Diagnostic Development: Potential use as a component in fluorescent immunoassays or biosensors that utilize membrane-based detection platforms.
• Model Membrane Systems: Incorporation into supported lipid bilayers (SLBs) or giant unilamellar vesicles (GUVs) for controlled in vitro studies.

Basic Information

Product Name	Dansyl Phosphatidylethanolamine
CAS No.	37219-74-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,2-Diacyl-sn-glycero-3-phosphoethanolamine-N-(5-dimethylaminonaphthalene-1-sulfonyl); DPE; Dansyl-DHPE; Dansyl PE; N-(5-Dimethylaminonaphthalene-1-sulfonyl)-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine; N-Dansyl Phosphatidylethanolamine; Fluorescent Phosphatidylethanolamine
EINECS	Contact for details

Quality Control

Our Dansyl Phosphatidylethanolamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and functional validation of fluorescence properties, to ensure consistency and performance for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific performance metrics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Upon receipt, the product should be stored desiccated and is stable for extended periods when kept frozen. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Solubility	Chloroform, Methanol, Ethanol
Fluorescence Properties	Excitation ~340 nm, Emission ~520 nm (solvent dependent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.