Description

D-Amino Acid Dehydrogenase is a highly specific oxidoreductase enzyme that catalyzes the oxidative deamination of D-amino acids, a critical reaction in stereoselective biochemical pathways. This enzyme is essential for research and industrial processes requiring precise chiral discrimination and the metabolism of D-amino acid isomers. It serves as a vital tool for biochemists, pharmaceutical researchers, and manufacturers in the fields of enzymatic synthesis, biosensor development, and diagnostic reagent production.

Application

• Enzymatic Assay Kits & Diagnostic Reagents: A key component in clinical and research assay kits for the specific detection and quantification of D-amino acids, which are biomarkers for various physiological and pathological conditions.
• Pharmaceutical Intermediate Synthesis: Used in the stereoselective synthesis of chiral intermediates for active pharmaceutical ingredients (APIs), where control over the D-isomer is crucial.
• Biosensor Development: Immobilized on electrodes or other transducers to create highly selective biosensors for real-time monitoring of D-amino acids in fermentation broths or biological samples.
• Biocatalysis & Green Chemistry: Employed in environmentally friendly catalytic processes to produce enantiomerically pure compounds, reducing the need for harsh chemical reagents.
• Microbiological & Food Science Research: Used to study bacterial cell wall metabolism (e.g., in peptidoglycan synthesis) and to analyze D-amino acid content in food products for quality and safety.
• Neuroscience Research: Facilitates studies on the role of D-serine and other D-amino acids as neuromodulators in the central nervous system.

Basic Information

Item	Detail
Product Name	D-Amino Acid Dehydrogenase
CAS No.	37205-44-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	D-Amino-Acid Dehydrogenase; D-AADH; D-Amino Acid Oxidase (common misnomer, related activity); EC 1.4.99.1 (provisional); D-Amino Acid:(Acceptor) Oxidoreductase (Deaminating); D-Amino Acid Dehydrogenase (FAD-Independent)
EINECS	Contact for details

Quality Control

Our D-Amino Acid Dehydrogenase is produced and tested under stringent quality management systems. Each batch is characterized for specific activity, purity, and stability to ensure reproducible and reliable performance in your applications. Certificates of Analysis (COA) detailing assay results, protein content, and specific activity are provided with every shipment. We adhere to relevant guidelines for enzymatic and biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. Avoid repeated freeze-thaw cycles to maintain optimal enzymatic activity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Activity)	Catalyzes oxidation of specific D-amino acid(s)
Specific Activity	> [Value] units/mg protein
Protein Content (Biuret)	> [Value] %
Purity (SDS-PAGE)	Single major band
Stability	Retains >90% activity after specified storage period
Solubility	Soluble in appropriate buffer (e.g., phosphate buffer, pH 7-8)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.