Description

Gtp, [γ-32P], Disodium Salt is a high-specific-activity, radiolabeled nucleotide essential for biochemical research and diagnostic development. Its core value lies in enabling the sensitive detection and quantification of enzymatic activities, particularly kinases and ATPases, through autoradiography and scintillation counting. This product is critically needed by researchers in molecular biology, pharmacology, and clinical diagnostics for studying signal transduction pathways, drug discovery, and developing novel assays.

Application

• Biochemical Research: As a high-energy phosphate donor in kinase assays to study phosphorylation events and enzyme kinetics.
• Molecular Biology: For nucleic acid labeling, filter-binding assays, and studying ATP-dependent processes like DNA replication and repair.
• Drug Discovery & Pharmacology: Used in high-throughput screening (HTS) to identify and characterize potential kinase inhibitors and other drug candidates.
• Diagnostic Development: Employed in the research and development of radioimmunoassays (RIAs) and other clinical diagnostic tests.
• Cellular Signaling Studies: To trace and quantify ATP utilization in live cells or cell lysates for metabolic and signaling pathway analysis.

Basic Information

Product Name	Gtp, [γ-32P], Disodium Salt
CAS No.	37156-72-2
Molecular Formula	C10H14N5O14P3•2Na
Molecular Weight	~529.1 g/mol (unlabeled salt)
Synonyms	Guanosine 5'-triphosphate, [γ-32P]-; [γ-32P]GTP; GTP γ-32P; 32P-labeled GTP; Guanosine-5'-triphosphate, disodium salt, (32P)-labeled; Radiolabeled GTP; P-32 GTP; Triphosphoric acid P'→P''-ester with guanosine 5'-ester, disodium salt, (32P)-
EINECS	Contact for details

Quality Control

Every batch of [γ-32P]GTP is manufactured and tested under strict quality systems to ensure high radiochemical purity and specific activity. Our quality control includes rigorous analysis for identity, purity, and radioactive concentration. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing the specific activity, radiochemical purity (typically >95% by HPLC), and expiration date. Production follows cGMP guidelines where applicable to support research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original lead-shielded container. This product is light-sensitive (store away from light) and must be handled with appropriate shielding and in accordance with all local and international regulations for radioactive materials. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Clear, colorless solution
Specific Activity	>5000 Ci/mmol
Radiochemical Purity (HPLC)	≥ 95%
Radioactive Concentration	~10 mCi/mL
Chemical Purity (HPLC)	≥ 98%
Identification (TLC/Co-chromatography)	Conforms
pH	6.0 - 8.0
Solvent	Aqueous buffer (e.g., Tricine)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.